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A rainbow of methods promises insights into biological processes and diseases
05-01-2007 · EurekAlert!This month's release of Cold Spring Harbor Protocols features freely available methods for marking molecules to identify gene alterations and metabolic shifts.
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Keywords: rainbow, methods, promises, insights, biological, processes, diseases, method, promise, insight, processe, disease
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- Cold Spring Harbor scientists devise novel, low-cost method of sifting genome's high-value regions
11-06-2007 · EurekAlert!
Scientists at Cold Spring Harbor Laboratory have developed a new means of extracting and interpreting data from the human genome that is more powerful and more economical than methods currently employed. The new technology, called selective resequencing, promises to be a boon to many kinds of research, including efforts to comb vast stretches of the genome for mutant genes implicated in major diseases such as cancer and schizophrenia.
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- Casting the molecular net
06-14-2007 · EurekAlert!
Scientists at the Samuel Lunenfeld Research Institute of Mount Sinai Hospital, European Molecular Biology Laboratory, and Massachusetts Institute of Technology have created a new computational method called NetworKIN. This method uses biological networks to better identify relationships between molecules. In a cover story featured in the June 29, 2007, edition of the journal Cell, the scientists report insights into the regulation of protein networks that will ultimately help to target human disease.
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- NIH researchers discover protein that appears to regulate bone mass loss, the cause of osteoporosis
03-05-2007 · EurekAlert!
An estimated ten million Americans suffer from osteoporosis, and another 34 million Americans are at risk of developing the disease. The basic mechanism behind osteoporosis involves an imbalance between bone mineral formation and loss, but the detailed biological processes that lead to this imbalance are not completely understood. Now researchers at NIAID and colleagues are reporting new insights into the biology of bone loss based on a study of 14 people with a rare genetic disorder called X-linked Hyper IgM Syndrome.
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- Landmark study details demographic, ecological and genetic spread of rabies in raccoon outbreak
05-17-2007 · EurekAlert!
Analyzing 30 years of data detailing a large rabies virus outbreak among North American raccoons, researchers have revealed how initial demographic, ecological and genetic processes simultaneously shaped the virus's geographic spread over time. These results provide important insights into the geographic scale of rabies persistence and will be increasingly important in understanding the epidemiology of rabies and other emerging zoonotic diseases.
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- Osteoarthritis May Be Sign Of Faster 'Biological Aging'
10-02-2006 · ScienceDaily
Osteoarthritis, the degenerative inflammatory bone disease, may be a sign of faster "biological aging," suggests research published ahead of print in the Annals of the Rheumatic Diseases. The authors base their findings on a study of almost 1100 people, aged between 30 and 79. Most of them were female twins.
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- Human embryonic stem cells derived from preimplantation genetically diagnosed embryos
11-14-2007 · EurekAlert!
A human stem cell line derived from embryos that were identified by preimplantation genetic diagnosis to carry the mutation for fragile X syndrome has provided an unprecedented view of early events associated with this disease. In addition to giving scientists fresh insight into fragile X, results from this unique model system have emphasized the value of this new source of embryonic stem cells and may have a significant impact on the way that genetic diseases are studied in the future.
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- Scripps Research scientists discover remarkable editing system for protein production
01-02-2008 · EurekAlert!
Even small mistakes made by cells during protein production can have profound disease effects, but the processes cells use to correct mistakes have been challenging to decipher. Recent work by scientists at The Scripps Research Institute, however, has uncovered two surprising new methods for such editing.
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- Omega-3 fatty acids protect eyes against retinopathy, study finds
06-24-2007 · EurekAlert!
This is the major finding of a study that appears in the July 2007 issue of the journal Nature Medicine. Paul A. Sieving, M.D., Ph.D., director of the NEI, said,"This study explores the potential benefit of dietary omega-3 fatty acids in protecting against the development and progression of retinal disease. The study gives us a better understanding of the biological processes that lead to retinopathy and how to intervene to prevent or slow disease."
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- Staph vaccine shows promise in mouse study
10-30-2006 · EurekAlert!
By combining four proteins of Staphylococcus aureus that individually generated the strongest immune response in mice, scientists have created a vaccine that significantly protects the animals from diverse strains of the bacterium that cause disease in humans. A report describing the University of Chicago study, funded by the National Institute of Allergy and Infectious Diseases of the National Institutes of Health, appears online this week in the Proceedings of the National Academy of Sciences.
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- New cause identified for necrotic enteritis in chicken
02-07-2008 · EurekAlert!
Researchers from Monash University and CSIRO Livestock Industries have demonstrated for the first time that alpha-toxin protein, long thought to be required for necrotic enteritis to develop, is not the main cause of the chicken disease. The study, published Feb. 8 in the open-access journal PLoS Pathogens, provides insight into one of the world's most common and financially crippling poultry diseases.
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