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Scripps research team sheds light on long-sought cold sensation gene
05-02-2007 · EurekAlert!For years, scientists have struggled to identify the genes responsible for mammals' sensation of cold. Finally, scientists from The Scripps Research Institute and the Novartis Research Foundation have shown that a gene called TRPM8 is responsible for the bulk of this ability in mice.
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- Scripps Research scientists reveal pivotal hearing structure
09-05-2007 · EurekAlert!
A team of scientists made up of two laboratory groups from the Scripps Research Institute and one from the National Institutes of Health has shed light on how our bodies convert vibrations entering the ear into electrical signals that can be interpreted by the brain. Exactly how the electrical signal is generated has been the subject of ongoing research interest.
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- Scripps Research scientists shed new light on how antibodies fight HIV
09-06-2007 · EurekAlert!
Leading an international team of scientists, immunologists at the Scripps Research Institute have uncovered the first evidence that an HIV antibody is most effective when it binds not only to the virus, but also to host immune cells. The findings suggest that antibody efficiency depends on both directly neutralizing the virus and activating the host immune response.
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- New evidence shows New Madrid Seismic Zone may be cold and dying
12-11-2006 · EurekAlert!
New results about the temperatures of rock deep below the New Madrid Seismic Zone in the central United States shed light on the puzzling questions of why large earthquakes happened there in 1811 and 1812 and when they may happen again. A research team including a Northwestern University geologist found that thermally New Madrid is surprisingly similar to other areas of the eastern United States. New Madrid appears to be cold and dying, they report.
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- Scripps research study shows humans and plants share common regulatory pathway
04-09-2007 · EurekAlert!
In findings that some might find reminiscent of science fiction, scientists at the Scripps Research Institute have shown for the first time that humans and plants share a common pathogen recognition pathway as part of their innate immune systems. The data could help shed fresh light on how pathogen recognition proteins function and the role they play in certain chronic inflammatory diseases.
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- Molecule blocks gene, sheds light on liver cancer
08-01-2007 · EurekAlert!
New research shows how a particular small molecule blocks the activity of a cancer-suppressing gene, allowing liver cancer cells to grow and spread. This molecule is a microRNA, a recently discovered class of tiny molecules used by cells to help control the kinds and amounts of proteins they make. More than 250 different microRNAs have been discovered, and several have been linked to cancer.
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- CIHR news: U of S scientists find plant gene that affects stress resistance
01-25-2008 · EurekAlert!
A University of Saskatchewan team of scientists funded by the Canadian Institutes of Health Research has isolated a gene that has never before been identified in helping plants to resist stress.The study -- published this month in the top-ranked plant journal The Plant Cell -- could pave the way for development of agricultural and forestry crops that are more tolerant to environmental stresses such as ultraviolet light and other types of radiation.
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- Environmental epigenetics has potential for preventing and treating disease
01-31-2008 · EurekAlert!
New research on environmental influences on health and disease has begun to shed light on why genetically identical individuals demonstrate different characteristics, such as susceptibility to disease. Scientists have found that environmental exposure to nutritional, chemical and physical factors can alter the epigenome. Literally meaning "above the genome," the epigenome refers to differences in gene expression that are inherited without changing the sequence of DNA.
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- Non-steroidal anti-inflammatory drug increases liver damage in mice carrying mutant human gene
11-15-2006 · EurekAlert!
Research performed at Washington University School of Medicine in St. Louis sheds light on the mechanisms that contribute to liver disease in alpha-1-AT deficiency patients. People with alpha-1-deficiency have a genetic mutation that can lead to emphysema at an early age and to liver damage. Using an experimental mouse model of the disorder, the researchers investigated the effects of a non-steroidal anti-inflammatory drug on liver injury.
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Using a variety of new approaches, scientists at Scripps Institution of Oceanography at UC San Diego are forging a new understanding of the largest mammals on Earth.
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01-26-2007 · EurekAlert!
New findings by a Saint Louis University researcher shed light on the genetic risk some of us have for developing diabetes.
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