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Cancer cells 'reprogram' energy needs to grow and spread, study suggests
05-07-2007 · EurekAlert!Studying a rare inherited syndrome, researchers at Johns Hopkins have found that cancer cells can reprogram themselves to turn down their own energy-making machinery and use less oxygen, and that these changes might help cancer cells survive and spread.
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Keywords: cancer, cells, reprogram, energy, needs, grow, spread, study, suggests, cell, need, suggest
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- Study says normal but out-of-control enzyme may be culprit that signals some cells to become cancer
07-31-2007 · EurekAlert!
Working with human colorectal cancer cells, a University of Minnesota team, led by cancer biologists Zigang Dong and Ann Bode, has found the potential culprit among a network of enzymes that relay signals inside cells to regulate such functions as cell growth, cancer development and programmed cell death. The work suggests that drugs designed to disable the enzyme, known as TOPK, could have anticancer benefits. The study appears in the July issue of the journal Gastroenterology.
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- Standard treatment for prostate cancer may encourage spread of disease
10-01-2007 · EurekAlert!
A popular prostate cancer treatment called androgen deprivation therapy may encourage prostate cancer cells to produce a protein that makes them more likely to spread throughout the body, a new study by Johns Hopkins researchers suggests.
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- Transparent zebrafish help researchers track breast cancer
10-22-2007 · EurekAlert!
What if doctors could peer through a patient's skin and see a cancer tumor growing? They'd be able to study how tumor cells migrate: how they look, how they interact with the blood system to find nourishment to grow and spread through the body. Scientists at the UCSD School of Medicine can't look through human skin. But a small, tropical minnow fish common to aquariums has given researchers a window for viewing live, human cancer cells in action.
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- Bacteria join ranks of lazy cheaters
09-24-2007 · EurekAlert!
A new study has discovered that one type of bacteria has mutants that shut down certain communication systems so they don't have to share the communal burden of obtaining nutrients. This "cheating" mechanism forces other bacteria do all the work while the lazy bacteria save their energy, grow faster and out-compete other cells. The findings could suggest new concepts for antibiotic development.
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- Study: cow-powered fuel cells grow smaller, mightier
08-21-2007 · EurekAlert!
Cows could one day help to meet the rise in demand for alternative energy sources, say Ohio State University researchers that used microbe-rich fluid from a cow to generate electricity in a small fuel cell. This new microbial fuel cell is a redesign of a larger model that the researchers created a few years ago. The new cell is a quarter of the size of the original model, yet can produce about three times the power.
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- 2 microRNAs promote spread of tumor cells
01-28-2008 · EurekAlert!
Scientists at The Wistar Institute and their colleagues have identified two microRNAs that promote tumors' deadly spread. One of the miRNAs may provide an early warning of metastatic breast cancer and the need for aggressive treatment. In a study to be published Feb. 1 in Nature Cell Biology that is available online, the researchers describe how two miRNAs transformed non-invasive human breast cancer cells into cells that rapidly metastasized in cell cultures and mice.
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- Study proposes new theory of how viruses may contribute to cancer
10-23-2007 · EurekAlert!
A study published in the Oct. 24 issue of PLoS ONE suggests that viruses may contribute to cancer by causing excessive death to normal cells while promoting the growth of surviving cells with cancerous traits. The University of Pittsburgh Cancer Institute researchers suggest that viruses may act as forces of natural selection by wiping out normal cells that support the replication of viruses, leaving behind those cells that have acquired defects in their circuitry.
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- University of Pittsburgh scientists find new contributor to aggressive cancers
06-06-2007 · EurekAlert!
Mutations in the cell adhesion molecule known as integrin alpha 7 (integrin б7) lead to unchecked tumor cell proliferation and a significantly higher incidence in cancer spread, or metastasis, in several cancer cell lines, report researchers at the University of Pittsburgh School of Medicine in a study being published today in the Journal of the National Cancer Institute. These findings suggest that integrin б7 represents an important new target for cancer therapy and prevention.
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- Kaposi sarcoma arises independently from multiple cells
07-10-2007 · EurekAlert!
Kaposi sarcoma is unique among cancers because most tumors grow from a small number of different cells, whereas nearly all other cancers arise from a single cell, according to a study published online July 10 in the Journal of the National Cancer Institute.
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- Stress hormone may hasten the progression of certain blood cancers
11-19-2007 · EurekAlert!
Researchers here have shown that in cell cultures, the stress hormone norepinephrine appears to promote the biochemical signals that stimulate certain tumor cells to grow and spread. The finding, if verified, may suggest a way of slowing the progression and spread of some cancers enough so that conventional chemotherapeutic treatments would have a better chance to work.
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