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The yin and the yang of B-cell development

A new paper in the May 15 issue of Genes & Development reveals how a protein called Yin Yang 1 regulates early B cell development.

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Keywords: yin, yang, b-cell, development, cell

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1. UCLA researchers discover novel pathway that may promote immune system balance
   06-07-2007 · EurekAlert!
   Researchers at UCLA's Jonsson Cancer Center have discovered a novel anti-inflammatory cell signaling pathway that may serve as a vital Yin-Yang mechanism to maintain the delicate balance of immune response.
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2. Tissue Geometry Plays Crucial Role In Breast Cell Invasion
   10-13-2006 · ScienceDaily
   Researchers with the U.S. Department of Energy's Lawrence Berkeley National Laboratory have created a first-of-its-kind model for studying how breast tissue is shaped and structured during development. The model may shed new light on how the misbehavior of only a few cells can facilitate metastatic invasion because it shows that the development of breast tissue, normal or abnormal, is controlled not only by genetics, but also by geometry.
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3. Researchers find 'zip code' spurs cargo transport in neurons
   10-24-2006 · EurekAlert!
   Getting molecular cargo from the cell body to the synapse of nerve cells is crucial for learning and memory, even for survival of the cell itself. New research conducted at Brown University and the Marine Biological Laboratory in Woods Hole, Mass., shows that a single peptide can load and direct this biological material. This peptide "ZIP Code" comes from amyloid precursor protein, the principal player in the development of Alzheimer's disease.
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4. Research yields new insights into the cause of diabetes
   12-05-2006 · EurekAlert!
   The cause of insulin-dependent, permanent diabetes in newborn babies may be a deficiency in the PERK enzyme during a critical period of development before birth, according to a new hypothesis be published in the journal Cell Metabolism on Dec. 6, 2006. Using special strains of mice bred to be PERK-deficient, the researchers found that what happens during fetal development predisposes people either to be able to maintain glucose levels normally or to have diabetes.
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5. A study by the MUHC and McGill University opens a new door to understanding cancer
   08-09-2007 · EurekAlert!
   An in-depth understanding of the mechanisms that trigger cancer cell growth is vital to the development of more targeted treatments for the disease. An article published in the Aug. 3 issue of Molecular Cell provides a key to these mechanisms that may prove crucial in the future. The paper is co-authored by Dr. Morag Park, director of the MUHC Molecular Oncology Group, and Dr. Kalle Gehring, head of the Nuclear Magnetic Resonance Laboratory of the McGill University biochemistry department.
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6. New cell death pathway involved in sperm development
   09-17-2007 · EurekAlert!
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7. St. Jude identifies the specific cell that causes eye cancer, disproving long-held theory
   10-18-2007 · EurekAlert!
   Investigators at St. Jude Children's Research Hospital have identified the cell that gives rise to the eye cancer retinoblastoma, disproving a long-standing principle of nerve growth and development.
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8. Team of scientists develops non-invasive method to track nerve-cell development in live human brain
   11-08-2007 · EurekAlert!
   A team of scientists including researchers at Cold Spring Harbor Laboratory have identified and validated the first biomarker that permits neural stem and progenitor cells to be tracked, non-invasively, in the brains of living human subjects. This important advance could lead to significantly better diagnosis and monitoring of brain tumors and a range of serious neurological and psychiatric disorders.
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9. Gene Key To Taste Bud Development Identified
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   Scientists have identified a gene that controls the development of taste buds. The gene, SOX2, stimulates stem cells on the surface of the embryonic tongue and in the back of the mouth to transform into taste buds, according to the researchers. Stem cells are immature cells that can develop into several different cell types depending on what biochemical instructions they receive.
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10. Propane fuel cell passes muster at Exit Glacier Nature Center
    11-10-2006 · EurekAlert!
    The Alaska Energy Technology Development Laboratory at the University of Alaska Fairbanks recently announced a successful field test of a prototype propane fuel cell.
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