science top stories popular news  

Daily non-political popular news in brief.

Mechanism of microRNAs deciphered

05-16-2007 · EurekAlert!

Researchers from the European Molecular Biology Laboratory (EMBL) have developed a new method that uncovered the mode of action of microRNAs in a test tube. The study, which is published in the current online issue of Nature, reveals that microRNAs block the initiation of translation, the earliest step in the process that turns genetic information stored on messenger RNAs into proteins.

Read more »

Keywords: mechanism, micrornas, deciphered, microrna

« Previous | Next »

Similar news on "Mechanism of microRNAs deciphered":

  1. Expression patterns of microRNAs appear altered in colon cancer, and associated with poor outcomes
    01-29-2008 · EurekAlert!
    Preliminary research has found an association between certain microRNA expression patterns and poor survival and treatment outcomes for colon cancer, according to a study in the Jan. 30 issue of JAMA.
    Similar news · Read more »
  2. MicroRNA works with Ago2 protein to regulate blood cell development
    07-26-2007 · EurekAlert!
    MicroRNAs became the stars of the RNA universe, when scientists found that these short RNAs can control whether or not genes are expressed. Provocative new findings cast new light on the genesis of these key biological regulators and how they carry out their function.
    Similar news · Read more »
  3. Molecules may help predict survival in liver cancer
    01-30-2008 · EurekAlert!
    Tiny molecules that help cells regulate which proteins they make might one day help doctors predict which liver-cancer patients are likely to live longer than others. Researchers compared levels of microRNA in tumor cells and adjacent nontumor cells from liver-cancer patients, most of whom also had hepatitis and cirrhosis. Patients with poor disease-free survival had low overall levels of 19 particular microRNAs compared with those showing better survival after 16 years of follow-up.
    Similar news · Read more »
  4. Molecule blocks gene, sheds light on liver cancer
    08-01-2007 · EurekAlert!
    New research shows how a particular small molecule blocks the activity of a cancer-suppressing gene, allowing liver cancer cells to grow and spread. This molecule is a microRNA, a recently discovered class of tiny molecules used by cells to help control the kinds and amounts of proteins they make. More than 250 different microRNAs have been discovered, and several have been linked to cancer.
    Similar news · Read more »
  5. Dartmouth researchers find the root of the evolutionary emergence of vertebrates
    02-11-2008 · EurekAlert!
    Dartmouth College researchers and colleagues from the University of Bristol in the U.K. have traced the beginnings of complex life, i.e. vertebrates, to microRNA. The researchers argue that the evolution of microRNAs, which regulate gene expression, are behind the origin of early vertebrates.
    Similar news · Read more »
  6. MicroRNA convicted of triggering metastasis
    09-26-2007 · EurekAlert!
    While past studies have shown that some microRNAs cause normal cells to divide rapidly and form tumors, this one offers proof that a microRNA can also cause tumors to metastasize. It establishes an important new role for a class of RNA molecules whose significance was discovered only recently.
    Similar news · Read more »
  7. MicroRNAs may be key to HIV's ability to hide, evade drugs, Jefferson scientists find
    09-30-2007 · EurekAlert!
    Tiny pieces of genetic material called microRNA could be key to HIV's ability to evade detection in the immune system. Researchers have shown that when an HIV-infected individual receives a powerful cocktail of antiviral agents called HAART, the virus uses miRNAs to help it hide and remain practically undetectable, temporarily shutting down its ability to replicate. Learning to manipulate miRNA's inhibitory effects might have implications for new strategies against the virus.
    Similar news · Read more »
  8. Massive microRNA scan uncovers leads to treating muscle degeneration
    10-17-2007 · EurekAlert!
    An increasing number of genes have been linked to muscular dystrophy and related disorders that cause muscle weakness and wasting, but it's still largely unknown how these genes cause disease, and, more importantly, how to translate the discoveries into treatments. A report in PNAS this week finds a wealth of new clues about how muscle function is regulated by analyzing microRNAs -- tiny bits of code that govern gene expression.
    Similar news · Read more »
  9. Scientists decipher mechanism behind antimicrobial 'hole punchers'
    09-20-2007 · EurekAlert!
    In the battle against bacteria, researchers have scored a direct hit. They have deciphered the molecular mechanism behind selective antimicrobial activity for a prototypical class of synthetic compounds.
    Similar news · Read more »
  10. MicroRNA regulates cancer stem cells
    12-13-2007 · EurekAlert!
    Researchers have discovered a key molecular switch that regulates cancer stem cells. This switch, which belongs to a class of molecules called microRNAs, can decrease a cancer stem cell's ability to propagate tumors. These findings offer a way for targeting cancer stem cells directly, and as a result open up new avenues for potentially treating cancer as a whole.
    Similar news · Read more »