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Developments in tissue engineering offer new sources for stem cell treatments
05-21-2007 · EurekAlert!Tissue engineering and regenerative medicine offer future patients greater options for treatment and cure of a wide array of urologic conditions, and controversies surrounding the sources of stem cells as well as their use have fueled increased research. A special session for media highlighting this research was held on May 21 at 9:00 a.m. PDT.
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Keywords: developments, tissue, engineering, offer, sources, stem, cell, treatments, development, source, treatment
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- Replacing the cells lost in Parkinson disease
12-03-2007 · EurekAlert!
Parkinson disease is caused by the progressive degeneration of dopamine brain cells. Replacing these cells is considered a promising therapeutic strategy. Although DA cell-replacement therapy by transplantation of human fetal mesencephalic tissue has shown promise, limited tissue availability means other sources of these cells are needed. A recent study has described one new source for DA cells that provided marked benefit when transplanted into mice with a PD-like disease.
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- Engineered blood vessels function like native tissue
07-05-2007 · EurekAlert!
Blood vessels that have been tissue-engineered from bone marrow adult stem cells may in the future serve as a patient's own source of new blood vessels following a coronary bypass or other procedures that require vessel replacement, according to new research from the University at Buffalo Department of Chemical and Biological Engineering.
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- First human trial tests stem-cell-based treatment for heart attacks
03-25-2007 · EurekAlert!
Previous research on the efficacy of stem cell therapy for heart repair has shown possible benefit from mesenchymal stem cells (MSCs) -- cells found in bone marrow that create connective tissue, bone and cartilage. A study presented today at the American College of Cardiology's Innovation in Intervention: i2 Summit reveals the results of the first human trial using MSCs for the treatment of myocardial infarction (MI, or heart attack).
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- Adult stem cell application effective in treatment of peripheric vascular disease
01-24-2008 · EurekAlert!
Multipotent adult progenitor stem cells extracted from bone marrow, and known as MAPCs, have proved to be effective in the regeneration of blood vessel tissue and also in muscle tissue when treating peripheric vascular disease.
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- Muscle stem cells may offer a new treatment option for congestive heart failure
03-25-2007 · EurekAlert!
As a new wave of stem cell research continues, cardiologists are trying to tap into the self-renewing cells' life-saving potential. Scientists have performed the first US controlled, randomized Phase I clinical trial using a three-dimensional guided catheter system to deliver muscular stem cells to the heart. The study was presented today at the American College of Cardiology's Innovation in Intervention: i2 Summit in New Orleans.
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- New hope for regenerative medicine
02-14-2007 · EurekAlert!
In the February 15th issue of Genes & Development, Dr. K. John McLaughlin and colleagues report on their success in using uniparental embryonic stem cells to replace blood stem cells in mice. Uniparental embryonic stem cells are an appealing alternative source of patient-derived embryonic stem cells, as they have several advantages over embryonic stem cell lines generated by somatic cell nuclear transfer (also known as therapeutic cloning).
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- Cell growth technology promises more successful drug development
09-18-2007 · EurekAlert!
Scientists have developed unique technology to grow stem cells and other tissue in the laboratory in conditions similar to the way they grow in the human body. The technology, developed and patented by scientists at Durham University, UK, and its spin-out company ReInnervate Limited, is a plastic scaffold which allows cells to be grown in a more realistic three-dimensional form compared to the traditional flat surface of a Petri dish.
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- Scientists take next step in understanding potential target for Ovarian cancer treatment
07-16-2007 · EurekAlert!
A traffic cop protein in the cell may have an even more important role: transporting a messenger protein that tells components in the nucleus to stop cell growth. Scientists are studying the normal function of a protein called 'km23', the traffic cop protein, because the team previously found altered forms of the protein in 42 percent of tumor tissue samples taken from women with Ovarian cancer. The discovery of this additional role may lead to diagnostic tools and earlier treatments for Ovarian cancer.
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- Pediatric cancer stem cell identified: understanding the origin of ERMS
05-16-2007 · EurekAlert!
As published in the June 1 issue of Genes & Development, Dr. Leonard Zon (Children's Hospital Boston) and colleagues have identified the cancer stem cell for rhabdomyosarcoma, the most common soft-tissue sarcoma of childhood.
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- Study shows isolation of stem cells may lead to a treatment for hearing loss
04-05-2007 · EurekAlert!
Members of the National Center for Regenerative Medicine research team, Dr. Robert Miller and Dr. Kumar Alagramam, both of Case Western Reserve University School of Medicine, published research findings in Developmental Neuroscience which suggest new ways of treating hearing loss. These researchers have isolated "cochlear stem cells" located in the inner ear and already primed for development into ear-related tissue due to their proximity to the ear and expression of certain genes necessary for the development of hearing.
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