Daily non-political popular news in brief.
UF researchers awaken vision cells in blind mice
05-21-2007 · EurekAlert!Scientists describe how they used a harmless virus to deliver corrective genes to mice with a genetic impairment that robs them of vision. The discovery shows that it is possible to target and rescue cone cells -- the most important cells for visual sharpness and color vision in people.
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Keywords: researchers, awaken, vision, cells, blind, mice, researcher, cell
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- Stem-cell transplantation improves muscles in animal model of muscular dystrophy, researchers report
01-21-2008 · UT Southwestern Medical Center
Using embryonic stem cells from mice, UT Southwestern Medical Center researchers have prompted the growth of healthy — and more importantly, functioning — muscle cells in mice afflicted with a human model of Duchenne muscular dystrophy.
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- Penn Veterinary Medicine report new strategy to create genetically-modified animals
09-20-2007 · EurekAlert!
Researchers at Penn Vet have demonstrated a new strategy for genetic modification of large animals by employing a virus that transfers genetic modifications to male reproductive cells, which passes naturally to offspring. Scientists at the Center for Animal Transgenesis and Germ Cell Research at Penn introduced adeno-associated virus to germline stem cells in goats and mice. AAV stably transduced male germ line stem cells and led to transgene transmission through the male germ line.
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- Penn Veterinary Medicine report new strategy to create genetically modified animals
09-20-2007 · EurekAlert!
Researchers at Penn Vet have demonstrated a new strategy for genetic modification of large animals by employing a virus that transfers genetic modifications to male reproductive cells, which passes naturally to offspring. Scientists at the Center for Animal Transgenesis and Germ Cell Research at Penn introduced adeno-associated virus to germline stem cells in goats and mice. AAV stably transduced male germ line stem cells and led to transgene transmission through the male germ line.
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- 2 microRNAs promote spread of tumor cells
01-28-2008 · EurekAlert!
Scientists at The Wistar Institute and their colleagues have identified two microRNAs that promote tumors' deadly spread. One of the miRNAs may provide an early warning of metastatic breast cancer and the need for aggressive treatment. In a study to be published Feb. 1 in Nature Cell Biology that is available online, the researchers describe how two miRNAs transformed non-invasive human breast cancer cells into cells that rapidly metastasized in cell cultures and mice.
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- See How They See: Immature cells boost vision in night-blind mice
11-11-2006 · Science News Online
Transplanted retinal cells can restore some vision in mice with degenerative eye disease.
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- MIT corrects sickle-cell anemia in mice
12-07-2007 · Massachusetts Institute of Technology (MIT)
MIT researchers have successfully treated mice with sickle-cell anemia in a process that begins by directly reprogramming the mice's own cells to an embryonic-stem-cell-like state, without the use of eggs.
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- U of MN adult stem cell research shows promise for transplant therapies
01-15-2007 · EurekAlert!
University of Minnesota stem cell researchers, together with collaborators at Stanford University, have successfully used adult stem cells to replace the immune system and bone marrow of mice, offering the promise of new therapies for people in the future.
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- Loss of stem cells correlates with premature aging in animal study
06-06-2007 · EurekAlert!
Researchers at the Abramson Family Cancer Research Institute of the University of Pennsylvania have found that deleting a gene important in embryo development leads to premature aging and loss of stem cell reservoirs in adult mice. This gene, ATR, is essential for the body's response to damaged DNA, and mutations in proteins in the DNA damage response underlie certain types of cancer and other disorders in humans.
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- T vs. B: Re-engineered human T cells effectively target and kill cancerous B cells
09-18-2007 · EurekAlert!
Human white blood cells, engineered to recognize other malignant immune cells, could provide a novel therapy for patients with highly lethal B cell cancers such as acute lymphoblastic leukemia, according to researchers at Memorial Sloan-Kettering Cancer Center. By administering repeated doses of T cells designed to express an artificial receptor which recognizes human B cells, the researchers were able to eradicate cancer in 44 percent of mice bearing human ALL tumors.
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- Mass. General researchers identify master cardiac stem cell
11-22-2006 · EurekAlert!
Researchers from the Massachusetts General Hospital Cardiovascular Research Center have discovered what appears to be a master cardiac stem cell, capable of differentiating into the three major cell types of the mammalian heart. In a report to appear in the journal Cell, receiving early online release, they describe identifying these progenitor cells in mice, cloning them from embryonic stem cells, and showing that cloned cells can differentiate into cardiac muscle, smooth muscle or endothelial cells.
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