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MIT reports key pathway in synaptic plasticity

Scientists are keenly studying how neurons form synapses -- the physical and chemical connections between neurons -- and the "pruning" of neural circuits during development, not least because synaptic abnormalities may partially underlie many developmental and neurodegenerative diseases. Several key molecules are involved in normal synaptic formation, but their interactions are not well understood. Now MIT neuroscientists have pieced together a direct linear pathway connecting three such molecules.

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