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Fat stem cells being studied as option for breast reconstruction
10-26-2006 · EurekAlert!Breast cancer survivors might one day avoid the prospect of invasive breast reconstruction surgery, opting instead for an approach that would involve using stem cells from their own fat, suggest researchers who are studying the potential these cells may have for regenerating new breast tissue. In animal models, they hope to prove that an injection of fat stem cells that are seeded onto microscopic scaffold structures will enable production of durable, replacement soft tissue.
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Keywords: fat, stem, cells, studied, option, breast, reconstruction, cell
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- Study questions 'cancer stem cell' hypothesis in breast cancer
03-12-2007 · EurekAlert!
A Dana-Farber Cancer Institute study challenges the hypothesis that "cancer stem cells" -- a small number of self-renewing cells within a tumor -- are responsible for breast cancer progression and recurrence, and that wiping out these cells alone could cure the disease.
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- Signaling for cartilage
11-27-2006 · EurekAlert!
Skeletal progenitor cells differentiate into cartilage cells when one master gene actually suppresses the action of another. Skeletons are made of bone and cartilage cells that are differentiated from the same multipotent stem cell, which gives rise to bone, cartilage, fat and fibroblasts.
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- Cancer stem cells can go it alone
06-11-2007 · EurekAlert!
At the heart of most, if not all cancers, lie a handful of wayward stem cells that feed the ever growing tumor mass, but their scarcity make it difficult for scientists to study them. Now, times of plenty may lie ahead as a breast cancer cell line -- established long ago -- turned out to behave a lot like cancer stem cells.
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- Other highlights in the December 20 JNCI
12-19-2006 · EurekAlert!
Also in the December 20 issue of JNCI -- A report on breast cancer stem cells and radiation; research connecting statin use and advanced prostate cancer; a study of asthma medication and pancreatic cancer cell growth; and a model that predicts the risks of radiation therapy for leukemia patients.
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- Cancer cells enlist adult stem cells to promote metastasis
10-31-2007 · Massachusetts Institute of Technology (MIT)
MIT and Whitehead institute scientists have managed to facilitate metastasis, finding evidence that some breast cancer cells recruit normal adult stem cells from bone marrow and force them to secrete a protein that fosters cancer cell movement and invasion.
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- Muscle stem cells may offer a new treatment option for congestive heart failure
03-25-2007 · EurekAlert!
As a new wave of stem cell research continues, cardiologists are trying to tap into the self-renewing cells' life-saving potential. Scientists have performed the first US controlled, randomized Phase I clinical trial using a three-dimensional guided catheter system to deliver muscular stem cells to the heart. The study was presented today at the American College of Cardiology's Innovation in Intervention: i2 Summit in New Orleans.
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- JCI table of contents: Feb. 1, 2007
02-01-2007 · EurekAlert!
This release contains summaries, links to PDFs and contact information for the following newsworthy papers to be published Feb. 1, 2007, in the JCI, including: New role in asthma for old drug; Tumor-reactive T cells boosted by hematopoietic stem cell transplantation; p21 stops HIV-1 in its tracks in hematopoietic stem cells; What makes epithelial cells change their identity?; NOTCHing up heart development; Stress response prevents neurodegeneration, and 4E-BP1 and 4E-BP2 stop mice getting fat.
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- Human embryonic stem cells derived from preimplantation genetically diagnosed embryos
11-14-2007 · EurekAlert!
A human stem cell line derived from embryos that were identified by preimplantation genetic diagnosis to carry the mutation for fragile X syndrome has provided an unprecedented view of early events associated with this disease. In addition to giving scientists fresh insight into fragile X, results from this unique model system have emphasized the value of this new source of embryonic stem cells and may have a significant impact on the way that genetic diseases are studied in the future.
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- Master regulatory gene of epithelial stem cells identified
05-03-2007 · EurekAlert!
The skin's ability to replace the tissue it sloughs off is controlled by a variety of genes. A new study from Harvard Medical School published in the May 4 issue of Cell, however, identifies a "master regulator" of this regeneration process not only for skin, but for many epithelial tissues including breast, prostate, and urogenital tract. This master regulator of epithelial stem cells turns out to be the p63 gene, a close relative to the well-known tumor-suppressing p53 gene.
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- Scientists identify a mouse embryonic stem cell more like our own
06-27-2007 · EurekAlert!
Scientists have discovered a new type of mouse embryonic stem cell that is the closest counterpart yet to human embryonic stem cells, the National Institutes of Health announced today. The cells are expected to serve as an improved model for human ES cells in studies of regeneration, disease pathology and basic stem cell biology.
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