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Adult brain cells rediscover their inner child
05-23-2007 · EurekAlert!Johns Hopkins researchers have found that newly made nerves in an adult brain's learning center experience a one-month period when they are just as active as the nerves in a developing child. The study, appearing this week in Neuron, suggests that new adult nerves have a deeper role than simply replacing dead ones.
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Keywords: adult, brain, cells, rediscover, inner, child, cell
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- Experimental anti-cancer drug made from corn lillies kills brain tumor stem cells
08-30-2007 · EurekAlert!
A drug that shuts down a critical cell-signaling pathway in the most common and aggressive type of adult brain cancer successfully kills cancer stem cells thought to fuel tumor growth and help cancers evade drug and radiation therapy, a Johns Hopkins study shows.
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- UCSF stem cell study reveals cells' capability in mouse brain tissue repair
12-14-2006 · EurekAlert!
UCSF scientists have determined that adult stem cells in a specific region of the mouse brain have a built-in mechanism that allows the cells to participate in the repair and remodeling of damaged tissue in the region.
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- Insight into neural stem cells has implications for designing therapies
07-05-2007 · EurekAlert!
Scientists have discovered that adult neural stem cells, which exist in the brain throughout life, are not a single, homogeneous group. Instead, they are a diverse group of cells, each capable of giving rise to specific types of neurons. The finding, the team says, significantly shifts the perspective on how these cells could be used to develop cell-based brain therapies.
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- Brain stem cells limited for replacement therapies
11-30-2007 · Massachusetts Institute of Technology (MIT)
MIT scientists report that adult stem cells produced in the brain are preprogrammed to make only certain kinds of connections--making it impossible for a neural stem cell originating in the brain to be transplanted to other regions.
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- HIV is a 'double hit' to the brain
08-15-2007 · EurekAlert!
New evidence reported in the August issue of Cell Stem Cell, a publication of Cell Press, offers a novel perspective on how the HIV/AIDS virus leads to learning and memory deficits, a condition known as HIV-associated dementia. A protein found on the surface of the virus not only kills some mature brain cells, as earlier studies had shown, but it also prevents the birth of new brain cells by crippling "adult neural progenitors," the new study finds.
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- AIDS interferes with stem cells in the brain
08-15-2007 · EurekAlert!
Scientists at the Burnham Institute for Medical Research have discovered how HIV/AIDS disrupts the normal replication of stem cells in the adult brain, preventing new nerve cells from forming. Drs. Stuart Lipton, Marcus Kaul, Shu-ichi Okamoto and colleagues uncovered a novel molecular mechanism that inhibits stem cell proliferation and that could possibly be triggered in other neurodegenerative diseases. These findings were published today online by the journal Cell Stem Cell.
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- Antidepressants stimulate new nerve cells in adult monkeys, may have implications for humans
05-04-2007 · EurekAlert!
In adult monkeys, an antidepressant treatment has induced new nerve cell growth in the hippocampus, a brain area responsible for learning and memory. A similar process may occur in humans, the research suggests, and may help explain the effectiveness of antidepressant treatments.
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- Cloned Mice Created From Fully Differentiated Cells, A Milestone In Cloning Research
10-02-2006 · ScienceDaily
New research dismisses the notion that adult stem cells are necessary for successful animal cloning, proving instead that cells that have completely evolved to a specific type not only can be used for cloning purposes, but they may be better and more efficient. As proof, researchers report they created two mouse pups from a type of blood cell that itself is incapable of dividing to produce a second generation of its own kind.
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- Mice cloned from skin cells
02-12-2007 · EurekAlert!
Healthy and viable mice that survive until adulthood have, for the first time, been cloned from adult stem cells. The scientists used keratinocyte stem cells, which represent a new model system for cloning. Keratinocytes come from the skin, making them a particularly attractive stem cell source because of their ready accessibility. One day, they could be used to tailor therapies, as well as to better understand and treat diseases.
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- Simple recipe turns human skin cells into embryonic stem cell-like cells
11-20-2007 · EurekAlert!
A simple recipe -- including just four ingredients -- can transform adult human skin cells into cells that resemble embryonic stem cells, researchers report in an immediate early publication of the journal Cell, a publication of Cell Press. The converted cells have many of the physical, growth and genetic features typically found in embryonic stem cells and can differentiate to produce other tissue types, including neurons and heart tissue, according to the researchers.
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