Daily non-political popular news in brief.

Crohn's disease gene identified

10-26-2006 · EurekAlert!

Alterations in the receptor for a known inflammatory response pathway are strongly associated with Crohn's disease and ulcerative colitis, according to a report by a consortium of American and Canadian researchers in the Oct. 26 online edition of Science.

Keywords: crohn, disease, gene, identified

« Previous | Next »

Similar news on "Crohn's disease gene identified":

Researchers find gene linked to Crohn's disease
10-26-2006 · EurekAlert!
An international team of researchers has identified another gene mutation linked to the inflammatory bowel diseases (IBD) Crohn's disease and ulcerative colitis. The team, including Johns Hopkins gastroenterologists and geneticists, says the novel mutation is in the interleukin-23 (IL-23) gene receptor present in healthy people without Crohn's disease but rare in those with the disease.
Similar news · Read more »
New gene found for Crohn's disease
10-26-2006 · EurekAlert!
A new gene associated with Crohn's disease has been identified by a team of researchers. Interestingly, one of the mutations in the gene, which codes for a receptor in a major inflammatory pathway, appears to confer significant protection against the disease. The finding, the researchers report, points to a crucial target for drugs that might better manage both Crohn's and ulcerative colitis, which affect more than one million Americans.
Similar news · Read more »
Gene identified for Crohn's disease in children
07-18-2007 · EurekAlert!
Pediatrics researchers have identified a gene variant that raises a child’s risk of Crohn's disease, a chronic and painful condition attributed to inflammation of the gastrointestinal tract. Because multiple genes interact with each other and with environmental factors in Crohn's disease, sorting out the roles of specific genes may better enable doctors to classify a patient's genetic profile and guide individualized treatment.
Similar news · Read more »
Research team identifies additional genetic risk factors for Crohn's disease
04-15-2007 · EurekAlert!
An international research team has identified several novel genetic variations associated with the risk of Crohn's disease. One of the identified genes establishes a role for autophagy, a previously unsuspected biological pathway, in Crohn's disease pathology, and the report documents functional studies which establish that this gene is integral to immune responses to intestinal bacteria.
Similar news · Read more »
Scientists find major susceptibility gene for Crohn's disease
04-15-2007 · EurekAlert!
Using a novel approach, researchers identified that the PHOX2B, NCF4 and ATG16L1 genes constitute genetic risk factors for Crohn's disease. In addition, their study identified two regions of the genome where genetic risk factors are located but no known genes were implicated -- further work will be necessary to identify the causal genes in these regions.
Similar news · Read more »
Life-threatening gene defect located by UT-Houston researchers
11-11-2007 · EurekAlert!
Scientists at The University of Texas Medical School at Houston have identified a defective gene that affects vascular smooth-muscle cells in people who suffer from hereditary thoracic aortic disease, which can kill victims with little warning in the prime of their lives.
Similar news · Read more »
Lupus gene finding prompts call for more DNA samples
12-02-2007 · EurekAlert!
Wellcome Trust researchers have identified a key gene involved in the disease lupus, which affects around 50,000 people in the UK, mostly women. The lead researcher behind the study has called for more patients to volunteer DNA samples to enable them to further study the underlying causes of the disease.
Similar news · Read more »
New cataract gene discovered
02-14-2008 · EurekAlert!
Researchers at ETH Zurich and the University Zurich have identified the chromosomal location and exact molecular defect in the coding region of the gene responsible for a childhood cataract. Until now, no human disease could be associated with this gene. The researchers' results will be published in the American Journal of Human Genetics.
Similar news · Read more »
Cedars-Sinai researchers on multicenter team linking gene mutation to Crohn's disease
10-26-2006 · EurekAlert!
The North American IBD Genetics Consortium has linked a gene mutation to the development of Crohn's disease, a chronic, relapsing inflammatory disorder of the gastrointestinal tract that affects 100 to 150 of every 100,000 people of European ancestry. The consortium is composed of IBD genetics research groups from seven centers in North America, including Cedars-Sinai Medical Center, and this effort was led by teams at Yale University and the University of Pittsburgh.
Similar news · Read more »
Il-22 gene delivers the goods and decreases intestinal inflammation
01-02-2008 · EurekAlert!
There are two major types of inflammatory bowel disease, Crohn disease and ulcerative colitis. Conflicting reports have indicated the soluble factor IL-22 can have both IBD promoting and IBD controlling effects. A new study has, however, now indicated that local delivery of the Il-22 gene ameliorates disease in a mouse model of UC, leading to the suggestion that individuals with UC might benefit from local delivery of the IL-22 gene to their intestines.
Similar news · Read more »