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Common treatment for methamphetamine overdose may damage brain cells
05-29-2007 · EurekAlert!A common antipsychotic drug used in emergency rooms to treat methamphetamine overdose damages nerve cells in an area of the brain known to regulate movement, a new study shows.
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Keywords: treatment, methamphetamine, overdose, damage, brain, cells, cell
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- Neural stem cells lend the brain a surprising capacity for self-repair
12-14-2006 · EurekAlert!
The brain contains stem cells with a surprising capacity for repair, researchers report in the Dec. 15 issue of the journal Cell, published by Cell Press. The novel insight into the brain's natural ability to heal might ultimately have clinical implications for the treatment of brain damage, according to the researchers.
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- Common cancer treatments toxic to healthy brain cells
11-29-2006 · EurekAlert!
Common drugs used to treat cancer may be more harmful to healthy brain cells than the cancer cells that they are intended to destroy, according to a new study. The results, which also indicate that chemotherapy may cause long-term brain damage, represent the closest that scientists have come to pinpointing the underlying physiological cause of "chemo brain," a common side effect of cancer treatment that scientists are only now beginning to comprehend.
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- Antidepressants stimulate new nerve cells in adult monkeys, may have implications for humans
05-04-2007 · EurekAlert!
In adult monkeys, an antidepressant treatment has induced new nerve cell growth in the hippocampus, a brain area responsible for learning and memory. A similar process may occur in humans, the research suggests, and may help explain the effectiveness of antidepressant treatments.
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- Evidence found for novel brain cell communication
07-16-2007 · EurekAlert!
An article published today, July 16, 2007, in Proceedings of the National Academy of Sciences provides strong evidence for a novel type of communication between nerve cells in the brain. The findings may have relevance for the prevention and treatment of epilepsy, and possibly in the exploration of other aspects of brain functions, from creative thought processes to mental illnesses such as schizophrenia. The discovery suggests the first new model of brain function since the 1940s.
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- Epilepsy-induced brain cell damage prevented in the laboratory
10-29-2007 · EurekAlert!
For some epilepsy patients, the condition's side effects can be as troubling as the seizures. One pressing concern is potential cognitive impairment from seizures, which can include memory loss, slowed reactions and reduced attention spans. Now researchers have linked such cognitive impairments to structural changes in brain cells caused by seizures. They report that the insights they gained allowed them to use a drug to block those changes in the brains of laboratory animals.
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- Treatment capitalizes on unique qualities of radioisotope to prolong lives of brain tumor patients
01-30-2008 · EurekAlert!
In a study to determine safe dosages of the isotope astatine-211 for patients with recurring brain tumors, researchers were pleasantly surprised to find that not only was the isotope's potency sufficient to kill residual cancer cells without damaging sensitive healthy brain cells, but the patients experienced longer survival rates.
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- VEGF neutralization can damage brain vessels, say Schepens Eye Research Institute scientists
02-12-2008 · EurekAlert!
New research by scientists at Schepens Eye Research Institute may help explain why the anticancer drug Avastin, which targets a growth factor responsible for creation of new blood vessels, causes potentially fatal brain inflammation in certain patients. Institute scientists mimicked the drug's activity in mice and found that it damaged the cell lining that prevents fluid from leaking from the ventricle into the brain.
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- Custom-made cancer cell attacks
02-16-2007 · EurekAlert!
Imagine a cancer treatment tailored to the cells in a patient’s body, each person receiving a unique treatment program. This is what Natural Sciences and Engineering Research Council grantee Thomas Ruth and his colleagues hope to accomplish within the next decade. Using the TRIUMF particle accelerator based in Vancouver, British Columbia, they are taking vast amounts of radioactive material and separating the particular atoms they need for therapy
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- Why cisplatin kills breast cancer cells when other drugs fail
04-19-2007 · EurekAlert!
The cancerous cells of some individuals with breast cancer lack expression of two cell surface proteins, the estrogen and progesterone receptors, and do not express increased amounts of HER2. Individuals with such breast cancer (known as triple-negative breast cancer) do not respond to treatment with commonly used chemotherapeutic drugs and their prognosis is relatively poor. But a new study has indicated why triple-negative breast cancer cell lines are sensitive to exposure to the chemotherapeutic cisplatin.
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- Electrical activity alters language used by nerve cells
12-19-2006 · EurekAlert!
University of California, San Diego biologists have shown that the chemical language with which neurons communicate depends on the pattern of electrical activity in the developing nervous system. The findings suggest that modification of nerve activity could have potential as a treatment for a wide range of brain disorders.
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